Treatment The Food and Drug Administration (FDA) has issued Emergency Use Authorization (EUA) to allow the use of monoclonal antibody therapies for the treatment of mild to moderate COVID-19 in certain high-risk patients. Visit our monoclonal antibody therapy page for more information. Most people with illnesses caused by coronaviruses like COVID-19 will recover on their own. However, there are some things you can do to relieve your symptoms, including: Taking pain and fever medications (caution: do not give aspirin to children). Using a humidifier or taking a hot shower to ease a sore throat and cough. Drinking plenty of liquids and stay home and rest. Follow instructions from your local health department and health care provider for appropriate care. Additional medications and treatments for COVID-19 are being investigated, including through clinical trials in North Carolina and across the nation. A clinical trial is a type of research study used to test if a drug or medical device is both safe and effective for human use. Registered trials for drugs being studied for the prevention or treatment of COVID-19 can be found at ClinicalTrials.gov. To find clinical trials happening specifically in NC, you may specify your search through ClinicalTrials.gov by location. Additionally, many academic medical centers update clinical trials occurring at their institutions on their respective websites. Frequently Asked Questions What treatments are available? For non-hospitalized patients who are experiencing mild to moderate symptoms of COVID-19, monoclonal antibodies, currently available under emergency use authorization, may be a treatment option. Click here to learn more about monoclonal antibody therapy. (link to new MAB page) For patients with more severe COVID-19, hospitals can provide care. Veklury® (Remdesivir) is FDA approved for the treatment of COVID-19 in hospitalized patients 12 years of age and older who weigh at least 40 kg. There is more to be learned about COVID-19 as the situation continues to evolve, and treatment options may change over time. Learn more from the CDC. Is a vaccine available? Yes. Three vaccines from Pfizer-BioNTech, Moderna and Johnson & Johnson (Janssen) have proven to provide significant protection against COVID-19 and protect against virus-related hospitalization and death, with no serious safety concerns in the clinical trials. Visit the webpage on vaccines for the latest information. What is hydroxychloroquine (Plaquenil) and does it treat COVID-19? Hydroxychloroquine is approved by the U.S. Food and Drug Administration to treat lupus and rheumatoid arthritis, as well as treat or prevent malaria. On June 15, 2020, the U.S Food and Drug Administration revoked the emergency use authorization for hydroxychloroquine sulfate and chloroquine phosphate to treat COVID-19. According to this latest information, the Food and Drug Administration has determined that hydroxychloroquine warrants revocation of the emergency use authorization, due to ongoing serious cardiac adverse events and other serious side effects. Read the press release. What other medications are being tested to treat COVID-19? Many medications are being tested to treat or prevent COVID-19, but no medication is currently approved by the FDA to treat the virus. Many of the medications in testing for COVID-19 are FDA approved to treat serious diseases, such as tuberculosis, HIV infection and autoimmune conditions. It is important that those medications remain available to treat the conditions for which they are FDA approved as their effectiveness for COVID-19 is being assessed. Learn more from the CDC. Are veterinary medications or other products with chloroquine as an active ingredient safe to consume? No. People should not take any medications unless they are FDA approved for human consumption and prescribed by their doctor. The Pet Industry Joint Advisory Council issued a statement reminding everyone “they should never use pet care products, or any products, for any purpose other than what the label directs.” Is there a definition of recovery from COVID-19? If I've had symptoms of COVID-19 when can I end self-isolation? A standardized definition of recovery from COVID-19 has not yet been established; it is a work in progress in North Carolina and at academic institutions across the country. As with other respiratory illnesses, how long a patient takes to return to feeling “normal” is highly variable and depends on many factors including severity of illness and underlying medical conditions, so a single time period cannot be applied to all people. View the COVID-19 Patients Presumed to be Recovered Report. It is important to understand the steps to ending self-isolation. Patients who have mild symptoms consistent with COVID-19 and can recover at home can return to normal activities when they can answer yes to the following three questions: Has it been at least 10 days since your symptoms started? Has it been 24 hours since you last had fever, without the use of fever-reducing medications? Have your symptoms, such as coughing and shortness of breath, improved? Notably, patients with clinical COVID-19 infection, in general, do NOT need a negative COVID-19 test result to document recovery, if they meet the clinical criteria. Read the CDC What to do if you are sick and the CDC guidance for ending isolation for more information.