Vaccination Information for Health Care Providers

Vaccination Information for Health Care Providers

Information, guidance and tools for vaccinating North Carolinians.

Interim Provider Guidance for Vaccinating North Carolinians

Following a thorough safety review, the Centers for Disease Control and Prevention and the Food and Drug Administration have confidence that the Johnson & Johnson vaccine is safe and effective in preventing COVID-19 and recommend its use to prevent serious illness, hospitalization and death from COVID-19. More information.

COVID-19 Vaccine Provider Guidance provides administrative guidance on vaccinating eligible North Carolinians.

Expiration Dates and COVID-19 Vaccines

The expiration date should be checked prior to preparing or administering vaccine. Expired vaccine or diluent should NEVER be used. As additional stability data become available, the expiration dates for some products may change.

For EUA COVID-19 vaccines that do not have a final expiration date, CDC has set up an expiration date of 12/31/2069 to serve as a placeholder date. Such vaccines have a dynamic expiration date, which can change over time as additional stability data become available. This placeholder date, which is far in the future, is intended to serve as a prompt for the provider to check the latest expiry information on the manufacturer’s website.

Moderna COVID-19 vaccine: To determine the expiration date, providers can scan the QR code located on the vial or carton or access the manufacturer’s website directly, enter the lot number and the expiration date will be displayed. CDC’s COVID-19 Vaccine Expiration Date Tracking Tool can help providers keep track of the expiration date by lot number.

Pfizer COVID-19 vaccine: This vaccine product has an expiration date located on the vaccine vial.


Vaccine safety has been and will continue to be one of CDC’s top priorities. Once COVID-19 vaccines are made available in the United States, CDC will rely on existing systems and a new system, v-safe, to monitor vaccine safety.

V-safe is a smartphone-based tool that uses text messaging and web surveys to provide personalized health check-ins after someone receives a COVID-19 vaccination. Through v-safe, vaccine recipients can quickly tell CDC if they have any side effects after getting the COVID-19 vaccine. Depending on their responses, CDC may follow up with them by phone to get more information. V-safe will also remind them to get their second COVID-19 vaccine dose, if needed.

Download v-safe print resources

Access Portals for Vaccine Enrollment and Reporting

Administering COVID-19 vaccines in North Carolina requires first that a provider enrolls with the State.  That process takes place in the Provider Enrollment Portal, at which time the individual provider will select which Vaccine Reporting System they would like to use, either the North Carolina Immunization Registry (NCIR) or the COVID-19 Vaccine Management System (CVMS).  Regardless of which Vaccine Reporting System a provider selects, they will both utilize the same Help Desk Portal for any questions they may have.

Learn to Use the Vaccine Reporting Systems

All providers must complete the enrollment in the Provider Enrollment Portal, after which they are then able to log vaccine administrations in their chosen Vaccine Reporting System.  Select the links below to learn more about the enrollment process, and the advantages of each reporting system.